Summary

Name ASCC3
Full Name Activating signal cointegrator 1 complex subunit 3
Synonyms ASC-1 complex subunit p200, ASC1p200, Helicase, ATP binding 1, Trip4 complex subunit p200 | HELIC1
Primary ID Q8N3C0
Links - -
Type protein
Relations 0
Function 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions (PubMed:22055184). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347).

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