Name
|
ASCC3
|
Full Name |
Activating signal cointegrator 1 complex subunit 3 |
Synonyms |
ASC-1 complex subunit p200, ASC1p200, Helicase, ATP binding 1, Trip4 complex subunit p200 | HELIC1 |
Primary ID |
Q8N3C0 |
Links |
- -  |
Type |
protein |
Relations |
0 |
Function |
3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions (PubMed:22055184). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). |