4.0
Summary
| Name |  IL17RD
|
| Full Name | Interleukin-17 receptor D |
| Synonyms | IL-17 receptor D, IL-17RD, IL17Rhom, Interleukin-17 receptor-like protein, Sef homolog, hSef | IL17RLM, SEF |
| Primary ID | Q8NFM7 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12958313, PubMed:12807873). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK (PubMed:15239952). Mediates JNK activation and may be involved in apoptosis (By similarity). May inhibit FGF-induced FGFR1 tyrosine phosphorylation (By similarity). Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). |