Summary

Name SUN3
Full Name SUN domain-containing protein 3
Synonyms Sad1/unc-84 domain-containing protein 1 | SUNC1
Primary ID Q8TAQ9
Links - -
Type protein
Relations 1
Function As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding LINC complex 0.413
Publications: 1