3.0
Summary
| Name |  ELP5
|
| Full Name | Elongator complex protein 5 |
| Synonyms | Dermal papilla-derived protein 6, S-phase 2 protein | C17orf81, DERP6 |
| Primary ID | Q8TE02 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). Involved in cell migration (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ELP5 | form complex 
binding
|
Elongator complex | 0.696 |
| Publications: | 1 | Organism: | Homo Sapiens | |