Summary

Name LMX1A
Full Name LIM homeobox transcription factor 1-alpha
Synonyms LIM/homeobox protein 1.1, LMX-1.1, LIM/homeobox protein LMX1A
Primary ID Q8TE12
Links - -
Type protein
Relations 2
Function Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding NLI/Lmx1.1/Isl1 0.349
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation CUX2 0.289
Publications: 1 Organism: Mus Musculus