4.0
Summary
| Name |  SLC5A11
|
| Full Name | Sodium/myo-inositol cotransporter 2 |
| Synonyms | Na(+)/myo-inositol cotransporter 2, Sodium-dependent glucose cotransporter, Sodium/glucose cotransporter KST1, Sodium/myo-inositol transporter 2, SMIT2, Solute carrier family 5 member 11 | KST1, SLGTX, SMIT2 |
| Primary ID | Q8WWX8 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. |