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Summary
Name
RXFP2
Full Name
Relaxin receptor 2
Synonyms
G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2 | GPR106, GREAT, LGR8
Primary ID
Q8WXD0
Links
-
-
Type
protein
Relations
1
Function
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
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by mechanism
none
binding
by effect
none
up-regulates
by organism:
none
Homo sapiens
by tissue:
none
brain
by cell-line
none
Relations
Regulator
Mechanism
target
score
ℹ
+
RLN2
up-regulates
binding
RXFP2
0.696
Identifier
Residue
Sequence
Organism
Cell Line
SIGNOR-114585
Homo sapiens
pmid
sentence
11809971
Lgr7 and lgr8, are capable of mediating the action of relaxin through an adenosine 3',5'-monophosphate (camp)-dependent pathway.
Publications:
1
Organism:
Homo Sapiens
Tissue:
Brain