Summary

Name PSPC1
Full Name Paraspeckle component 1
Synonyms Paraspeckle protein 1 | PSP1
Primary ID Q8WXF1
Links - -
Type protein
Relations 1
Function Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding LMX1B/SFPQ/PSPC1 complex 0.414
Publications: 1 Organism: Mus Musculus