Full Name Tumor necrosis factor receptor superfamily member 25
Synonyms Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1 | APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Primary ID Q93038
Links - -
Type protein
Relations 2
Function Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.



Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding TRADD 0.28
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding TNFRSF25 0.28
Publications: 1 Organism: Homo Sapiens