Summary

Name MYDGF
Full Name Myeloid-derived growth factor
Synonyms MYDGF, Interleukin-25, IL-25, Stromal cell-derived growth factor SF20 | C19orf10, IL25
Primary ID Q969H8
Links - -
Type protein
Relations 0
Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).

Viewer