Name
|
MYDGF
|
Full Name |
Myeloid-derived growth factor |
Synonyms |
MYDGF, Interleukin-25, IL-25, Stromal cell-derived growth factor SF20 | C19orf10, IL25 |
Primary ID |
Q969H8 |
Links |
- -  |
Type |
protein |
Relations |
0 |
Function |
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518). |