Summary

Name PLD4
Full Name 5'-3' exonuclease PLD4
Synonyms PLD 4, Choline phosphatase 4, Phosphatidylcholine-hydrolyzing phospholipase D4 | C14orf175
Primary ID Q96BZ4
Links - -
Type protein
Relations 0
Function 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.

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