Relation Results

Summary

Name BIRC7
Full Name Baculoviral IAP repeat-containing protein 7
Synonyms Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50 | KIAP, LIVIN, MLIAP, RNF50
Primary ID Q96CA5
Links - -
Type protein
Relations 2
Function Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell ...
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Type: Score: Layout: SPV 
0.6730.2BIRC7DIABLOUb:E2

Relations

Regulator
Mechanism
target
score
+ down-regulates img/direct_inhibition.png binding DIABLO 0.673
Identifier Residue Sequence Organism Cell Line
SIGNOR-129869 Homo sapiens Melanoma Cell
pmid sentence
These results suggest that ml-iap might regulate apoptosis by sequestering smac and preventing it from antagonizing xiap-mediated caspases, rather than by direct caspases.
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png ubiquitination BIRC7 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-271113 Homo sapiens
pmid sentence
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t
Publications: 1 Organism: Homo Sapiens
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