| Name
|
 TNIP3
|
| Full Name |
TNFAIP3-interacting protein 3 |
| Synonyms |
A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene protein | ABIN3, LIND |
| Primary ID |
Q96KP6 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
0 |
| Function |
Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding. |
4.0