Summary

Name GPHA2
Full Name Glycoprotein hormone alpha-2
Synonyms Putative secreted protein Zsig51, Thyrostimulin subunit alpha | GPA2, ZSIG51
Primary ID Q96T91
Links - -
Type protein
Relations 1
Function Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production (PubMed:12045258). Plays a central role in controlling thyroid cell metabolism (PubMed:12045258).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding TSHR 0.526
Publications: 1 Organism: Homo Sapiens