| + |
ARID3A | up-regulates quantity by expression 
transcriptional regulation
|
Immunoglobulin delta heavy chain |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268531 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 16738337 |
In this work, we show that TFII-I directly interacts with human Bright through amino acids in Bright's protein interaction domain and that specific tyrosine residues of TFII-I are essential for Bright-induced activity of an immunoglobulin reporter gene. Moreover, inhibition of TFII-I function in a B-cell line resulted in decreased heavy-chain transcript levels.| Figure 3 shows that both anti-Bright and anti-TFII-I precipitated the bf150 Bright binding site from the B-cell line but not from a T-cell line that contains but does not express the V1 gene. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GTF2I | up-regulates activity
binding
|
ARID3A |
0.358 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268533 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 16738337 |
In this work, we show that TFII-I directly interacts with human Bright through amino acids in Bright's protein interaction domain and that specific tyrosine residues of TFII-I are essential for Bright-induced activity of an immunoglobulin reporter gene. Moreover, inhibition of TFII-I function in a B-cell line resulted in decreased heavy-chain transcript levels. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ARID3A | up-regulates quantity by expression
transcriptional regulation
|
Immunoglobulin mu heavy chain |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-268532 |
|
|
Homo sapiens |
B-lymphocyte |
| pmid |
sentence |
| 16738337 |
In this work, we show that TFII-I directly interacts with human Bright through amino acids in Bright's protein interaction domain and that specific tyrosine residues of TFII-I are essential for Bright-induced activity of an immunoglobulin reporter gene. Moreover, inhibition of TFII-I function in a B-cell line resulted in decreased heavy-chain transcript levels.| Figure 3 shows that both anti-Bright and anti-TFII-I precipitated the bf150 Bright binding site from the B-cell line but not from a T-cell line that contains but does not express the V1 gene. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
ARID3A
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- 