Summary

Name H2AC14
Full Name Histone H2A type 1-J
Synonyms Histone H2A/e | H2AFE, HIST1H2AJ
Primary ID Q99878
Links - -
Type protein
Relations 2
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png monoubiquitination H2AC14 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png translation regulation H2AC14 0.2
Publications: 1 Organism: Homo Sapiens