Summary

Name SIGLEC1
Full Name Sialoadhesin
Synonyms Sialic acid-binding Ig-like lectin 1, Siglec-1 | SN
Primary ID Q9BZZ2
Links - -
Type protein
Relations 0
Function Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.

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