Summary

Name DPY30
Full Name Protein dpy-30 homolog
Synonyms Dpy-30-like protein, Dpy-30L
Primary ID Q9C005
Links - -
Type protein
Relations 1
Function As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.

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Relations

Regulator Mechanism target score ℹ
+ DPY30form complex img/form-complex.png binding MLL/SET subcomplex 0.89
Publications: 1 Organism: Homo Sapiens