4.0
Summary
| Name |  ZCWPW1
|
| Full Name | Zinc finger CW-type PWWP domain protein 1 |
| Synonyms | ZCPW1_HUMAN | |
| Primary ID | Q9H0M4 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Dual histone methylation reader specific for PRDM9-catalyzed histone marks (H3K4me3 and H3K36me3) (PubMed:32744506, PubMed:20826339). Facilitates the repair of PRDM9-induced meiotic double-strand breaks (DSBs) (By similarity). Essential for male fertility and spermatogenesis (By similarity). Required for meiosis prophase I progression in male but not in female germ cells (By similarity). |