Summary

Name GABARAPL1
Full Name Gamma-aminobutyric acid receptor-associated protein-like 1
Synonyms Early estrogen-regulated protein, GABA(A) receptor-associated protein-like 1, Glandular epithelial cell protein 1, GEC-1 | GEC1
Primary ID Q9H0R8
Links - -
Type protein
Relations 2
Pathways Autophagy
Function Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding GABARAPL1 0.97
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding SQSTM1
Publications: 1 Organism: Homo Sapiens
Pathways:Autophagy