Name
|
UNC93B1
|
Full Name |
Protein unc-93 homolog B1 |
Synonyms |
Unc-93B1, hUNC93B1 | UNC93, UNC93B |
Primary ID |
Q9H1C4 |
Links |
- -  |
Type |
protein |
Relations |
0 |
Function |
Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal. |