Summary

Name PORCN
Full Name Protein-serine O-palmitoleoyltransferase porcupine
Synonyms Protein MG61 | MG61, PORC, PPN
Primary ID Q9H237
Links - -
Type protein
Relations 1
Function Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png palmitoylation WNT3A 0.686
Publications: 1 Organism: Homo Sapiens