3.0
Summary
| Name |  DPH5View Modifications |
| Full Name | Diphthine methyl ester synthase |
| Synonyms | Diphthamide biosynthesis methyltransferase | |
| Primary ID | Q9H2P9 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis. |
methylation