4.0
Summary
| Name |  CIAO2A
|
| Full Name | Cytosolic iron-sulfur assembly component 2A |
| Synonyms | MIP18 family protein FAM96A | CIA2A, FAM96A |
| Primary ID | Q9H5X1 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CIAO2A | form complex 
binding
|
CIAO1-CIAO2A-CIAO3 cytosolic iron-sulfur protein assembly complex | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |