4.0
Summary
| Name |  EPG5
|
| Full Name | Ectopic P granules protein 5 homolog |
| Synonyms | EPG5_HUMAN | KIAA1632 |
| Primary ID | Q9HCE0 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located (PubMed:29130391). |