4.0
Summary
| Name |  UBN1
|
| Full Name | Ubinuclein-1 |
| Synonyms | HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein | |
| Primary ID | Q9NPG3 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | UBN1 | form complex 
binding
|
HIRA complex 1 | 0.727 |
| Publications: | 1 | Organism: | Homo Sapiens | |