RING finger protein 98, RING-type E3 ubiquitin transferase TRIM36, Tripartite motif-containing protein 36, Zinc-binding protein Rbcc728 | RBCC728, RNF98
Primary ID
Q9NQ86
Links
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Type
protein
Relations
1
Function
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation (PubMed:28087737). May play a role in the acrosome reaction and fertilization.
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t