4.0
Summary
| Name |  IGSF5
|
| Full Name | Immunoglobulin superfamily member 5 |
| Synonyms | IgSF5, Junctional adhesion molecule 4, JAM-4 | JAM4 |
| Primary ID | Q9NSI5 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). |