4.0
Summary
| Name |  PDS5B
|
| Full Name | Sister chromatid cohesion protein PDS5 homolog B |
| Synonyms | Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3 | APRIN, AS3, KIAA0979 |
| Primary ID | Q9NTI5 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | PDS5B | form complex 
binding
|
SHU complex | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |