Summary

Name INTS7
Full Name Integrator complex subunit 7
Synonyms Int7 | C1orf73
Primary ID Q9NVH2
Links - -
Type protein
Relations 1
Function Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Plays a role in DNA damage response (DDR) signaling during the S phase (PubMed:21659603). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267).

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Relations

Regulator Mechanism target score ℹ
+ INTS7form complex img/form-complex.png binding Integrator complex 0.78
Publications: 1 Organism: Drosophila Melanogaster