Summary

Name BEX4
Full Name Protein BEX4
Synonyms BEX1-like protein 1, Brain-expressed X-linked protein 4, Nerve growth factor receptor-associated protein 3 | BEXL1, NADE3
Primary ID Q9NWD9
Links - -
Type protein
Relations 1
Function May play a role in microtubule deacetylation by negatively regulating the SIRT2 deacetylase activity toward alpha-tubulin and thereby participate in the control of cell cycle progression and genomic stability (PubMed:27512957). In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates (By similarity). {ECO:0000250|UniProtKB:Q9CWT2, ECO:0000269|PubMed:27512957}.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation BEX4 0.2
Publications: 1 Organism: Homo Sapiens