Summary

Name DOK5
Full Name Docking protein 5
Synonyms Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6 | C20orf180
Primary ID Q9P104
Links - -
Type protein
Relations 2
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding DOK5 0.603
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png DOK5 0.382
Publications: 1 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle, Kidney