3.0
Summary
| Name |  ZBTB4View Modifications |
| Full Name | Zinc finger and BTB domain-containing protein 4 |
| Synonyms | KAISO-like zinc finger protein 1, KAISO-L1 | KIAA1538 |
| Primary ID | Q9P1Z0 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity). |
phosphorylation