| Name
|
 UBA2
|
| Full Name |
SUMO-activating enzyme subunit 2 |
| Synonyms |
Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2 | SAE2, UBLE1B |
| Primary ID |
Q9UBT2 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. |
3.0
binding