Relation Results

Summary

Name DNAH17
Full Name Dynein heavy chain 17, axonemal
Synonyms Axonemal beta dynein heavy chain 17, Axonemal dynein heavy chain-like protein 1, Ciliary dynein heavy chain 17, Ciliary dynein heavy chain-like protein 1, Dynein light chain 2, axonemal | DNAHL1, DNEL2
Primary ID Q9UFH2
Links - -
Type protein
Relations 1
Function Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dyne ...
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Type: Score: Layout: SPV 
0.7DNAH17Cilium_movement

Relations

Regulator
Mechanism
target
score
+ up-regulates img/indirect-activation.png Cilium_movement 0.7
Identifier Residue Sequence Organism Cell Line
SIGNOR-265549 Homo sapiens Spermatozoon
pmid sentence
Our study provides a comprehensive analysis of ODA heavy chain distribution in human spermatozoa and demonstrates the importance of DNAH17 (β-HC) in sperm flagellum structure and motility. We demonstrate that DNAH17 (β-HC) mutations are associated with a loss of ODAs and male infertility but not with PCD.
Publications: 1 Organism: Homo Sapiens
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