+ |
EIF2B4 | up-regulates activity
guanine nucleotide exchange factor
|
Ternary_GTP_eIF2_tRNA_complex |
0.765 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269142 |
|
|
Homo sapiens |
|
pmid |
sentence |
15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EIF2B4 | up-regulates activity
guanine nucleotide exchange factor
|
EIF2S2 |
0.744 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269132 |
|
|
Homo sapiens |
|
pmid |
sentence |
15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EIF2B4 | up-regulates activity
guanine nucleotide exchange factor
|
EIF2S1 |
0.864 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269127 |
|
|
Homo sapiens |
|
pmid |
sentence |
15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
GSK3B | down-regulates
binding
|
EIF2B4 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-175572 |
|
|
Homo sapiens |
|
pmid |
sentence |
21798082 |
Akt also promotes protein synthesis by phosphorylating and inactivating gsk3b, thus releasing the gsk3b-dependent inhibition of the eukariotic translation initiation factor 2b (eif2b). |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
EIF2B4 | up-regulates activity
guanine nucleotide exchange factor
|
EIF2S3 |
0.686 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-269137 |
|
|
Homo sapiens |
|
pmid |
sentence |
15054402 |
EIF2B converts the protein synthesis initiation factor 2 (eIF2) from an inactive GDP-bound form to an active eIF2-GTP complex owing to its guanine nucleotide exchange factor (GEF) activity. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |