3.0
Summary
| Name |  ATP5IF1
|
| Full Name | ATPase inhibitor, mitochondrial |
| Synonyms | Inhibitor of F(1)F(o)-ATPase, IF(1), IF1 | ATPI |
| Primary ID | Q9UII2 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | ATP5IF1 | form complex 
binding
|
ATP synthase | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |