Name
|
MAN1B1
|
Full Name |
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase |
Synonyms |
ER alpha-1,2-mannosidase, ER mannosidase 1, ERMan1, Man9GlcNAc2-specific-processing alpha-mannosidase, Mannosidase alpha class 1B member 1 | |
Primary ID |
Q9UKM7 |
Links |
- -  |
Type |
protein |
Relations |
0 |
Function |
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2). |