Summary

Name OGDHL
Full Name 2-oxoglutarate dehydrogenase-like, mitochondrial
Synonyms 2-oxoglutarate dehydrogenase complex component E1-like, OGDC-E1-like, Alpha-ketoglutarate dehydrogenase-like | KIAA1290
Primary ID Q9ULD0
Links - -
Type protein
Relations 1
Function 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH (By similarity). The OGDHC complex is mainly active in the mitochondrion (By similarity). Involved in the inhibition of cell proliferation and in apoptosis (PubMed:23152800, PubMed:31175094).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ OGDHLform complex img/form-complex.png binding OGDC 0.642
Publications: 1 Organism: Homo Sapiens