4.0
Summary
| Name |  MTUS1
|
| Full Name | Microtubule-associated tumor suppressor 1 |
| Synonyms | AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1 | ATBP, ATIP, GK1, KIAA1288, MTSG1 |
| Primary ID | Q9ULD2 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. |