4.0
Summary
| Name |  TNFSF13B
|
| Full Name | Tumor necrosis factor ligand superfamily member 13B |
| Synonyms | B lymphocyte stimulator, BLyS, B-cell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1 | BAFF, BLYS, TALL1, TNFSF20, ZTNF4 |
| Primary ID | Q9Y275 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Pathways | NF-KB Non Canonical |
| Function | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
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