Summary

Name DTX4
Full Name E3 ubiquitin-protein ligase DTX4
Synonyms Protein deltex-4, Deltex4, RING finger protein 155 | KIAA0937, RNF155
Primary ID Q9Y2E6
Links - -
Type protein
Relations 2
Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png ubiquitination DTX4 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png ubiquitination TBK1 0.567
Publications: 1 Organism: Homo Sapiens