Summary

Name CARD8
Full Name Caspase recruitment domain-containing protein 8
Synonyms Apoptotic protein NDPP1, CARD-inhibitor of NF-kappa-B-activating ligand, CARDINAL, DACAR, Tumor up-regulated CARD-containing antagonist of CASP9, TUCAN | KIAA0955, NDPP1
Primary ID Q9Y2G2
Links - -
Type protein
Relations 1
Function Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding CASP9 0.25
Publications: 1 Organism: Homo Sapiens