4.0
Summary
| Name |  NUBP2
|
| Full Name | Cytosolic Fe-S cluster assembly factor NUBP2 |
| Synonyms | Nucleotide-binding protein 2, NBP 2 | |
| Primary ID | Q9Y5Y2 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | NUBP2 | form complex 
binding
|
NUBP1-NUBP2 iron-sulfur cluster assembly scaffold complex | 0.599 |
| Publications: | 1 | |||