Summary

Name WSB1
Full Name WD repeat and SOCS box-containing protein 1
Synonyms WSB-1, SOCS box-containing WD protein SWiP-1 | SWIP1
Primary ID Q9Y6I7
Links - -
Type protein
Relations 1
Function Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png ubiquitination HIPK2 0.591
Publications: 1 Organism: Homo Sapiens