Summary

Name DGKB
Full Name Diacylglycerol kinase beta
Synonyms DAG kinase beta, 90 kDa diacylglycerol kinase, Diglyceride kinase beta, DGK-beta | DAGK2, KIAA0718
Primary ID Q9Y6T7
Links - -
Type protein
Relations 0
Function Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:11719522). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Has a higher activity with long-chain diacylglycerols like 1,2-di-(9Z-octadecenoyl)-sn-glycerol compared to 1,2-didecanoyl-sn-glycerol (By similarity). Specifically expressed in brain, it regulates neuron-specific morphological changes including neurite branching and neurite spine formation (By similarity).

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