Relation Results

Summary

Name CGB Family
Primary ID SIGNOR-PF108
Type protein family
Formed by CGB3; CGB5; CGB8, CGB7
Relations 2

Viewer

Type: Score: Layout: SPV 
0.20.2NANOGCGB FamilyLHCGR

Relations

Regulator
Mechanism
target
score
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation CGB Family 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-254624 Homo sapiens Embryonic Stem Cell, Embryonic Carcinoma Cell
pmid sentence
Transfection of NANOG-specific small interfering RNAs reduced levels of NANOG transcript and protein and induced activation of the extraembryonic endoderm-associated genes GATA4, GATA6, LAMININ B1, and AFP as well as upregulation of trophectoderm-associated genes CDX2, GATA2, hCG-alpha, and hCG-beta.
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LHCGR 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-69400 Homo sapiens
pmid sentence
The ?-Subunit of human choriogonadotropin interacts with the exodomain of the luteinizing hormone/choriogonadotropin receptor
Publications: 1 Organism: Homo Sapiens
a simple tooltip