Hippo Signaling

Pathway ID: SIGNOR-HPPView in NDEx

Description: The Hippo pathway controls organ size in diverse species by regulating cell proliferation, apoptosis, and stem cell self renewal. Actin cytoskeleton or cellular tension appears to be the master mediator that integrates and transmits upstream signals to the core Hippo signaling cascade.

Curated by: Milica Marinkovic

20 Seed Entities

Organism:
Name Primary ID
Mob1 SIGNOR-PF42
STK3/4 SIGNOR-PF41
Apoptosis SIGNOR-PH2
CTNNA1 P35221
SCF-betaTRCP SIGNOR-C5
Proliferation SIGNOR-PH4
SAV1 Q9H4B6
NF2 P35240
AMOT/MPP5/INADL/LIN7C SIGNOR-C27
WWTR1 Q9GZV5
Cell-Cell_contact SIGNOR-ST13
TEAD SIGNOR-PF22
TAOK SIGNOR-PF21
TJP2 Q9UDY2
14-3-3 SIGNOR-PF7
WWC1 Q8IX03
YAP1 P46937
CDH1 P12830
LATS1/2 SIGNOR-PF43
NEDD4L Q96PU5