| + |
BDH2 | down-regulates quantity 
chemical modification
|
(R)-3-hydroxybutyrate |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282514 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16380372 |
Human DHRS6 is a previously uncharacterized member of the short chain dehydrogenases/reductase family and displays significant homologies to bacterial hydroxybutyrate dehydrogenases. Substrate screening reveals sole NAD+-dependent conversion of (R)-hydroxybutyrate to acetoacetate with Km values of about 10 mm, consistent with plasma levels of circulating ketone bodies in situations of starvation or ketoacidosis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
(R)-3-hydroxybutyrate | up-regulates quantity 
precursor of
|
acetoacetate |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-282519 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 16380372 |
Human DHRS6 is a previously uncharacterized member of the short chain dehydrogenases/reductase family and displays significant homologies to bacterial hydroxybutyrate dehydrogenases. Substrate screening reveals sole NAD+-dependent conversion of (R)-hydroxybutyrate to acetoacetate with Km values of about 10 mm, consistent with plasma levels of circulating ketone bodies in situations of starvation or ketoacidosis. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
(R)-3-hydroxybutyrate