| + |
DGUOK | down-regulates quantity 
chemical modification
|
2'-deoxyinosine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280575 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17073823 |
DGUOK [dG (deoxyguanosine) kinase] is one of the two mitochondrial deoxynucleoside salvage pathway enzymes involved in precursor synthesis for mtDNA (mitochondrial DNA) replication. DGUOK is responsible for the initial rate-limiting phosphorylation of the purine deoxynucleosides, using a nucleoside triphosphate as phosphate donor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
2'-deoxyinosine | up-regulates quantity 
precursor of
|
2'-deoxyinosine 5'-phosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280577 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17073823 |
DGUOK [dG (deoxyguanosine) kinase] is one of the two mitochondrial deoxynucleoside salvage pathway enzymes involved in precursor synthesis for mtDNA (mitochondrial DNA) replication. DGUOK is responsible for the initial rate-limiting phosphorylation of the purine deoxynucleosides, using a nucleoside triphosphate as phosphate donor. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
hypoxanthine | up-regulates quantity
precursor of
|
2'-deoxyinosine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280556 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PNP | up-regulates quantity
chemical modification
|
2'-deoxyinosine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280555 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
2'-deoxyinosine